If CPP is left untreated
Central precocious puberty can have an impact on growth, development, and the psychosocial well-being of the child.
For untreated children, the long-term outcomes may include short stature, body disproportion, and obesity.
The association between early puberty and negative behavioral outcomes may be due to. 
- Lack of developmental readiness (i.e., children are not prepared for the sudden emotional and increased drive in adolescence)
- Psychological distress caused by developing earlier than their peers
Therefore, early diagnosis and adequate treatment are important to ensure that these children experience normal physical and psychological development.
Treatment continues for a finite time until the child reaches the age when puberty onset would occur naturally.
- Galván, A. 2017. Puberty. In: The Neuroscience of Adolescence (Cambridge Fundamentals of Neuroscience in Psychology). 1st ed. Cambridge: Cambridge University Press; 2017:21-49.
- Kaplowitz P, Bloch C. Evaluation and referral of children with signs of early puberty. Pediatrics. 2016;137(1):e20153732. doi:10.1542/peds. 2015-3732.
- Fensolvi® (leuprolide acetate) for injectable suspension 45 mg Prescribing Information. Dublin 2, Ireland: Tolmar International, Ltd.; 2020.
- Klein K, Soliman AM, Bonafede M, et al. Health Care Utilization and Economic Burden in Patients with Central Precocious Puberty: An Assessment of the Commercially Insured and Medicaid Populations. J Manag Care Spec Pharm. 2019;25(7):836-846. doi:10.18553/jmcp.2019.25.7.836