Is your Fensolvi correctly prepared? If not, go back to Preparing Fensolvi
Follow the step-by-step instructions below, or watch the full mixing & administration training video.
Step 1: Prepare all contents
On a clean field open both trays, discard the desiccant packs from each package and ensure all contents are in place.
You are now ready to assemble and mix Fensolvi.
Pull out (do NOT unscrew) the short blue plunger rod with attached gray stopper from Syringe B.
Discard both the blue plunger and attached grey stopper.
Gently screw the white plunger rod into the remaining gray stopper in Syringe B.
Step 2: Remove caps
Remove and discard caps from Syringe A and Syringe B.
Step 3: Join syringes
Join the two syringes together by pushing and gently screwing until secure.
Step 4: Mix contents
Inject the liquid contents of Syringe A into leuprolide acetate powder in Syringe B
Thoroughly mix the product for 45 seconds by pushing the contents back and forth to obtain a uniform suspension. (This is a great time to set expectations for the injection with the patient and caregivers).
When thoroughly mixed, the suspension will appear colorless to pale yellow.
NOTE: Product must be mixed as described. Shaking will NOT provide adequate mixing of the product.
Step 5: Draw all mixed product into Syringe B
After mixing, hold the syringes vertically (upright) with Syringe B (short, wide syringe) on the bottom. The syringes should remain securely coupled.
Draw all of the mixed product into Syringe B by depressing the Syringe A plunger and slightly withdrawing the Syringe B plunger.
Step 6: Uncouple syringes
Continue to hold syringes vertically (upright). Unscrew Syringe A to decouple the syringes while continuing to push down on the Syringe A plunger.
NOTE: Do not attempt to remove small air bubbles that remain in the formulation – this is acceptable for subcutaneous injections.
Step 7: Attach the sterile needle provided
Continue to hold Syringe B upright with the open end at the top.
Hold back the white plunger on Syringe B to prevent loss of the product and attach the safety needle cartridge. Gently screw clockwise with approximately a three-quarter turn until the needle is secure.
Do not overtighten, as the hub may become damaged resulting in leakage of the product during injection. The safety sheath may also be damaged if the needle is screwed with too much force.